Antidepressant properties: L-tryptophan functions as an effective antidepressant, promoting mood balance.
Nutraceutical value: It serves as a beneficial supplement in improving health and well-being.
Essential micronutrient: L-tryptophan is a vital micronutrient for both plants and humans.
Metabolic roles: It acts as a crucial metabolite in humans, plants, and microorganisms like Saccharomyces cerevisiae, Escherichia coli, and mice.
L-tryptophan is the L-form of tryptophan. It functions as an antidepressant, nutraceutical, micronutrient, and metabolite in humans, plants, and various organisms including Saccharomyces cerevisiae, Escherichia coli, and mice.
L-Tryptophan Chemical Properties
| Melting point | 289-290 °C (dec.)(lit.) |
| alpha | -31.1 º (c=1, H20) |
| Boiling point | 342.72°C (rough estimate) |
| density | 1.34 |
| bulk density | 400kg/m3 |
| refractive index | -32 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | 20% NH3: 0.1 g/mL at 20 °C, clear, colorless |
| form | powder |
| pka | 2.46(at 25℃) |
| color | White to yellow-white |
| PH | 5.5-7.0 (10g/l, H2O, 20℃) |
| Odor | wh. cryst. or cryst. odorless powd., sl. bitter taste |
| biological source | non-animal source |
| Optical Rotation | [α]20/D 31.5±1°, c = 1% in H2O |
| Water Solubility | 11.4 g/L (25 ºC) |
| Merck | 14,9797 |
| BRN | 86197 |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. |
| InChIKey | QIVBCDIJIAJPQS-VIFPVBQESA-N |
| LogP | 0.704 (est) |
| CAS DataBase Reference | 73-22-3(CAS DataBase Reference) |
| NIST Chemistry Reference | L-Tryptophan(73-22-3) |
| EPA Substance Registry System | L-Tryptophan (73-22-3) |
| Absorption | cut-off at 326nm in 0.5 M HCl at 0.5M |
Amino acid-based medication:
This drug is commonly used in amino acid infusions, often combined with iron and vitamins. When paired with vitamin B6, it can help alleviate depression and prevent or treat skin conditions. It also serves as a sedative for sleep, and when combined with L-dopa, it aids in the treatment of Parkinson’s disease. However, it is carcinogenic to experimental animals and may cause side effects such as nausea, loss of appetite, and asthma. Caution is advised when using it in combination with monoamine oxidase inhibitors.
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