Emergency Use: Methylprednisolone provides rapid relief in critical medical conditions, making it an essential drug in emergency management.
Versatile Treatment: It treats a wide range of conditions, including endocrine disorders, skin diseases, allergic reactions, and autoimmune disorders, offering broad therapeutic benefits.
Anti-Inflammatory Properties: As a corticosteroid, it effectively manages inflammation in diseases like arthritis, cerebral edema, and multiple neuritis, improving patient outcomes.
Chemotherapy Support: Methylprednisolone is also used to prevent chemotherapy-induced nausea and vomiting, enhancing patient comfort during treatment.
Methylprednisolone is a corticosteroid medication that falls under the glucocorticoid category. It is primarily used for the emergency management of severe medical conditions, offering rapid relief in critical situations. In addition to emergency use, it is also employed to treat a wide range of health issues, including endocrine disorders, rheumatic diseases, and collagen disorders.
Methylprednisolone is effective in managing skin conditions, allergic reactions, and various ophthalmic diseases. It is also prescribed for gastrointestinal diseases, certain blood disorders, and even leukemia. Furthermore, it plays a crucial role in managing shock, cerebral edema, multiple neuritis, and myelitis. Additionally, methylprednisolone is often utilized as a prophylactic treatment to prevent chemotherapy-induced nausea and vomiting.
Parameters
| Melting point | 228-237°C (dec.) |
| alpha | D20 +83° (dioxane) |
| Boiling point | 423.47°C (rough estimate) |
| density | 1.0868 (rough estimate) |
| refractive index | 82 ° (C=1, Dioxane) |
| storage temp. | 0-6°C |
| solubility | chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow |
| pka | 12.46±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 0.12g/L(25 ºC) |
| Merck | 146111 |
| BRN | 2340300 |
| BCS Class | 2 or 4? |
| InChIKey | VHRSUDSXCMQTMA-PJHHCJLFSA-N |
| CAS DataBase Reference | 83-43-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2) |
| EPA Substance Registry System | Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- (83-43-2) |
| Safety Information | |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-36-26 |
| WGK Germany | 2 |
| RTECS | TU4146000 |
| F | 39744 |
| HS Code | 2937290000 |
| Hazardous Substances Data | 83-43-2(Hazardous Substances Data) |
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