1. Broad Antibacterial Spectrum: Effective against both Gram-positive and Gram-negative bacteria, including tetracycline-resistant strains.
2. High Potency: Approximately ten times more potent than tetracycline, offering stronger antibacterial action.
3. Versatile Treatment: Used for a wide range of infections, including respiratory and urinary tract infections, as well as typhoid and mycoplasma pneumonia.
4. Good Solubility: Highly soluble in water, ensuring effective absorption and bioavailability for treatment.
Doxycycline hydrochloride, commonly referred to as doxycycline hydrochloride, is a crystalline powder that appears light blue or yellow. It is odorless, with a bitter taste, and has hygroscopic properties. The product is highly soluble in water and methanol, and only slightly soluble in ethanol and acetone. With a broad antibacterial spectrum, doxycycline hydrochloride is effective against both Gram-positive cocci and Gram-negative bacilli.
Its antibacterial activity is approximately ten times more potent than tetracycline and remains effective against tetracycline-resistant bacteria. It is primarily used in the treatment of respiratory tract infections, chronic bronchitis, pneumonia, and urinary tract infections. Additionally, it can be used for conditions such as macules, typhoid fever, and mycoplasma pneumonia.
Parameters
| Melting point | 195-201℃ |
| Fp | 87℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 50 mg/mL, clear, yellow-green |
| form | powder |
| color | yellow |
| biological source | synthetic |
| Water Solubility | Soluble in water. |
| BCS Class | 1 |
| InChIKey | RUYHIJHUVHIMIR-PGTYNCOMNA-N |
| SMILES | O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r| |
| CAS DataBase Reference | 10592-13-9(CAS DataBase Reference) |
| Safety Information | |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 3 |
| F | 8 |
| HS Code | 29413000 |
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